This will be dependant upon the environment the bag is to be used within, the risk factors the bag is exposed to and the fragility and sensitivity of the contents.
They would NOT be suitable for use in the hold of an aircraft or as a carrier transit solution, without additional external packaging.
They do offer a degree of shower/splash resistance but are not waterproof.
Perfect for a light weight storage and transit solution for equipment on and to site locations, as sample presentation and demonstration cases for reps.
Foam inserts can offer further protection to contents by restricting movement of the contents and also provide the benefit of the contents being easily identifiable and well organised at the point of use or display ensuring maximum work efficiency whether the contents are working tools, equipment or product samples for sales presentation and demonstrations.